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Evo AI Model: create new viruses that eliminate harmful bacteria

Researchers at Stanford University, in collaboration with the Arc Institute, have employed AI (Evo) to create novel viruses that target and eliminate harmful bacteria

Deeksha Upadhyay 22 September 2025 16:20

Evo AI Model: create new viruses that eliminate harmful bacteria

What Is It?

Evo is a substantial AI model developed using microbial and viral genetic sequences for genomics.

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Operates as a “ChatGPT for DNA,” forecasting, creating, and producing genetic sequences for synthetic biology uses.

Created By: Stanford University and Arc Institute.

Objective & Intent:

Design Therapeutic Viruses: Develop bacteriophages to combat drug-resistant infections.

Comprehend Mutations: Anticipate the effects of DNA mutations on protein activity and illness.

Speed up Innovation: Swap out sluggish trial-and-error lab processes for AI-powered design.

How Does It Function?

Training: Acquired knowledge from 80,000 microbial genomes and countless bacteriophage/plasmid sequences (approximately 300 billion nucleotides).

Pattern Recognition: Detects gene interactions, forecasts functional mutations.

Generative Design: Develops unique viral templates, proteins (such as Cas9 variants), and genome-wide structures.

Validation: Designs are created and evaluated in laboratories to validate biological function.

Essential Attributes:

Increased Context Length: Comprehends lengthy DNA sequences and interactions between genes.

Nucleotide-Level Precision: High accuracy at the scale of single base pairs.

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Generative Potential: Able to suggest novel protein variants and artificial genomes.

Accelerated R&D: Transforms years of research into weeks, minimizing expenses and duration.

Open Research: Accessible to the public for non-profit scholarly investigation.

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